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Online Library: Mortality

The following pages provide an overview of the most recent research and clinical studies about the health benefits of micronutrients in fighting Mortality. This collection of scientific facts proves that anyone who privately or publicly questions the health value of micronutrients does not serve YOUR health, or the health of the people, but rather the multi-billion dollar investment 'business with disease' based on patented pharmaceutical drugs.

We encourage you to forward the link to this important online library on natural health – one of the largest ones in the world – to your friends. You may also print out the articles you find most important for your own health condition and share them with your doctor. Any responsibly acting health professional will be grateful to receive such science-based health education.

Association of nut consumption with total and cause-specific mortality.


Author: Bao Y, Han J, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, Fuchs CS.

Affiliation: From the Channing Division of Network Medicine, Department of Medicine

Abstract: Increased nut consumption has been associated with a reduced risk of major chronic diseases, including cardiovascular disease and type 2 diabetes mellitus. However, the association between nut consumption and mortality remains unclear. The authors examined the association between nut consumption and subsequent total and cause-specific mortality among 76,464 women in the Nurses' Health Study (1980-2010) and 42,498 men in the Health Professionals Follow-up Study (1986-2010). Participants with a history of cancer, heart disease, or stroke were excluded. Nut consumption was assessed at baseline and updated every 2 to 4 years. During 3,038,853 person-years of follow-up, 16,200 women and 11,229 men died. Nut consumption was inversely associated with total mortality among both women and men, after adjustment for other known or suspected risk factors. Significant inverse associations were also observed between nut consumption and deaths due to cancer, heart disease, and respiratory disease. Conclusion: In two large, independent cohorts of nurses and other health professionals, the frequency of nut consumption was inversely associated with total and cause-specific mortality, independently of other predictors of death.

Calcium and vitamin D intake and mortality: results from the Canadian Multicentre Osteoporosis Study (CaMos).


Author: Langsetmo L, Berger C, Kreiger N, Kovacs CS, et al.

Affiliation: CaMos National Coordinating Centre (L.L., C.B.), McGill University, Montreal, Quebec H3A 1A1, Canada; University of Toronto (N.K., S.A.J., R.G.J.), Toronto, Ontario M5S 1A1, Canada; Memorial University (C.S.K.), St John's, Newfoundland A1B 3X7, Canada; University of Calgary (D.A.H.), Calgary, Alberta T2N 1N4, Canada; University of Saskatchewan (S.J.W.), Saskatoon, Saskatchewan S7N 5A2, Canada; McGill University (J.G., S.N.M., D.G.), Montreal, Quebec H3A 0G4, Canada; Osteoporosis and Metabolic Disease Program (A.H.), St Joseph's Health Center, London, Ontario N6A 4V2, Canada; University of British Columbia (J.C.P., B.L., M.S.P.), Vancouver, British Columbia V6T 1Z4, Canada; Laval University (J.P.B.), Quebec City, Quebec G1V 0A6, Canada; Queen's University (T.A., T.T.), Kingston, Ontario K7L 3N6, Canada; McMaster University (A.P., J.D.A.), Hamilton, Ontario L8S 4L8, Canada; University of Manitoba (W.D.L.), Winnipeg, Manitoba R3T 2N2, Canada; and University of Victoria (K.S.D.), Victoria, British Columbia V8P 5C2, Canada

Abstract: Calcium and vitamin D are recommended for bone health, but there are concerns about adverse risks. Some clinical studies suggest that calcium intake may be cardio protective, whereas others report increased risk associated with calcium supplements. Both low and high serum levels of 25-hydroxyvitamin D have been associated with increased mortality. The purpose of this study was to determine the association between total calcium and vitamin D intake and mortality and heterogeneity by source of intake. A total of 9033 participants with non-missing calcium and vitamin D intake data and follow-up were studied. Total calcium intake (dairy, non-dairy food, and supplements) and total vitamin D intake (milk, yogurt, and supplements) were recorded. There were 1160 deaths during the 10-year period. For women only, the authors found a possible benefit of higher total calcium intake and no evidence of heterogeneity by source; use of calcium supplements was also associated with reduced mortality for users vs non-users with statistically significant reductions remaining among those with doses up to 1000 mg/d. These associations were not modified by levels of concurrent vitamin D intake. No definitive associations were found among men. Conclusion: Calcium supplements, up to 1000 mg/d, and increased dietary intake of calcium may be associated with reduced risk of mortality in women. The authors found no evidence of mortality benefit or harm associated with vitamin D intake

High concentrations of a urinary biomarker of polyphenol intake are associated with decreased mortality in older adults.


Author: Zamora-Ros R, Rabassa M, Cherubini A, et al.

Affiliation: Nutrition and Food Science Department, Pharmacy School, University of Barcelona, Barcelona, Spain.

Abstract: Polyphenols might have a role in the prevention of several chronic diseases, but evaluating total dietary polyphenol (TDP) intake from self-reported questionnaires is inaccurate and unreliable. A promising alternative is to use total urinary polyphenol (TUP) concentration as a proxy measure of intake. The current study evaluated the relationship between TUPs and TDPs and all-cause mortality during a 12-y period among older adult participants. The study population included 807 men and women aged 65 y and older from the Invecchiare in Chianti study, a population-based cohort study of older adults living in the Chianti region of Tuscany, Italy. TUP concentrations were measured at enrolment (1998-2000) using the Folin-Ciocalteau assay after a solid-phase extraction. TDPs were also estimated at baseline throughout a validated food frequency questionnaire and using the authors’ database based on USDA and Phenol-Explorer databases. They modeled associations using Kaplan-Meier survival and Cox proportional hazards models, with adjustment for potential confounders. During the 12-y follow-up, 274 participants (34%) died. At enrollment, TUP excretion adjusted for age and sex tended to be greater in participants who survived than in those who died. However, no significant differences were observed for TDPs. In the multivariable Cox model, participants in the highest tertile of TUP at enrolment had a lower mortality rate than those in the lowest tertile, whereas no significant associations were found between TDP and overall mortality. Conclusion: TUP is an independent risk factor for mortality among community-dwelling older adults, suggesting that high dietary intake of polyphenols may be associated with longevity.