Online Library: Mixed Connective Tissue Disease
Vitamin D Supplementation may Benefit Patients with Mixed Connective Tissue Disease
Source: Autoimmun Rev, 2011; 10(6):317-324
Affiliation: Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Abstract: In a study involving 125 women with mixed connective tissue disease (MCTD) and 48 matched controls, results indicate a high prevalence of vitamin D insufficiency in MCTD patients, and an inverse association between vitamin D status in MCTD patients and risk of cardiovascular disease. The authors of this study conclude, "The prevalence of vitamin D insufficiency is high in patients with MCTD. We assume that vitamin D insufficiency along with inflammatory parameters and lipid abnormalities may provoke cardiovascular events."