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Online Library: Mixed Connective Tissue Disease

Vitamin D

Vitamin D Supplementation may Benefit Patients with Mixed Connective Tissue Disease

Source: Autoimmun Rev, 2011; 10(6):317-324

Author: Hajas A, Bodolay E, et al

Affiliation: Medical and Health Science Center, University of Debrecen, Debrecen, Hungary

Abstract: In a study involving 125 women with mixed connective tissue disease (MCTD) and 48 matched controls, results indicate a high prevalence of vitamin D insufficiency in MCTD patients, and an inverse association between vitamin D status in MCTD patients and risk of cardiovascular disease. The authors of this study conclude, "The prevalence of vitamin D insufficiency is high in patients with MCTD. We assume that vitamin D insufficiency along with inflammatory parameters and lipid abnormalities may provoke cardiovascular events."